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rabbit anti mouse caspase3 antibody  (R&D Systems)


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    R&D Systems rabbit anti mouse caspase3 antibody
    Rabbit Anti Mouse Caspase3 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 924 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+anti+human+caspase/pm41981447-165-20-25?v=R%26D+Systems
    Average 96 stars, based on 924 article reviews
    rabbit anti mouse caspase3 antibody - by Bioz Stars, 2026-07
    96/100 stars

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    Setd8 deficiency reduces RPC proliferation and promotes apoptosis (A and D) Representative retinal section images of YFP (green) and EdU (magenta) staining at P0 (A) and P2 (D) from Ctrl (left) and Setd8 cKO (right) mice. Scale bars, 50 μm. (B and E) Quantification of the number of YFP+ (left graph) or EdU+ (right graph) cells at P0 (B) and P2 (E) ( n = 15 from 5 retinas). ∗∗ p < 0.01. (C and F) Proportion of YFP+ EdU+ (double-positive) cells among YFP+ cells at P0 (C) and P2 (F) ( n = 15 from 5 retinas). ∗∗ p < 0.01. (G) Representative retinal section images of γH2AX (magenta) staining at P0 (left) and P2 (right) from Ctrl (upper) and Setd8 cKO (lower) mice. Scale bars, 50 μm. (H) Quantification of the number of γH2AX + cells at P0 and P2 ( n = 15 from 5 retinas). (I) Representative retinal section images of YFP (green) and <t>active</t> <t>caspase-3</t> (magenta) staining at P0 (left) and P2 (right) from Ctrl (upper) and Setd8 cKO (lower) mice. Scale bars, 50 μm. (J) Quantification of active caspase-3+ cells at P0 and P2 ( n = 15 from 5 retinas).
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    Image Search Results


    Setd8 deficiency reduces RPC proliferation and promotes apoptosis (A and D) Representative retinal section images of YFP (green) and EdU (magenta) staining at P0 (A) and P2 (D) from Ctrl (left) and Setd8 cKO (right) mice. Scale bars, 50 μm. (B and E) Quantification of the number of YFP+ (left graph) or EdU+ (right graph) cells at P0 (B) and P2 (E) ( n = 15 from 5 retinas). ∗∗ p < 0.01. (C and F) Proportion of YFP+ EdU+ (double-positive) cells among YFP+ cells at P0 (C) and P2 (F) ( n = 15 from 5 retinas). ∗∗ p < 0.01. (G) Representative retinal section images of γH2AX (magenta) staining at P0 (left) and P2 (right) from Ctrl (upper) and Setd8 cKO (lower) mice. Scale bars, 50 μm. (H) Quantification of the number of γH2AX + cells at P0 and P2 ( n = 15 from 5 retinas). (I) Representative retinal section images of YFP (green) and active caspase-3 (magenta) staining at P0 (left) and P2 (right) from Ctrl (upper) and Setd8 cKO (lower) mice. Scale bars, 50 μm. (J) Quantification of active caspase-3+ cells at P0 and P2 ( n = 15 from 5 retinas).

    Journal: Stem Cell Reports

    Article Title: Histone methyltransferase Setd8 preserves chromatin accessibility to safeguard retinal progenitor cell identity during development

    doi: 10.1016/j.stemcr.2025.102789

    Figure Lengend Snippet: Setd8 deficiency reduces RPC proliferation and promotes apoptosis (A and D) Representative retinal section images of YFP (green) and EdU (magenta) staining at P0 (A) and P2 (D) from Ctrl (left) and Setd8 cKO (right) mice. Scale bars, 50 μm. (B and E) Quantification of the number of YFP+ (left graph) or EdU+ (right graph) cells at P0 (B) and P2 (E) ( n = 15 from 5 retinas). ∗∗ p < 0.01. (C and F) Proportion of YFP+ EdU+ (double-positive) cells among YFP+ cells at P0 (C) and P2 (F) ( n = 15 from 5 retinas). ∗∗ p < 0.01. (G) Representative retinal section images of γH2AX (magenta) staining at P0 (left) and P2 (right) from Ctrl (upper) and Setd8 cKO (lower) mice. Scale bars, 50 μm. (H) Quantification of the number of γH2AX + cells at P0 and P2 ( n = 15 from 5 retinas). (I) Representative retinal section images of YFP (green) and active caspase-3 (magenta) staining at P0 (left) and P2 (right) from Ctrl (upper) and Setd8 cKO (lower) mice. Scale bars, 50 μm. (J) Quantification of active caspase-3+ cells at P0 and P2 ( n = 15 from 5 retinas).

    Article Snippet: The following primary antibodies were used: chicken anti-Nestin (1:500, NES, Aves Labs); goat anti-Sox2 (1:500, AF2018, R&D Systems); rabbit anti-active caspase 3 (1:500, AF-835, R&D Systems); chick anti-GFP (1:500, GFP-1010, Aves Labs); sheep anti-Chx10 (1:100, X1180P, Exalpha); rabbit anti-H4K20me1 (1:500, ab9051, Abcam); rabbit anti-S-opsin (1:500, AB5407, Millipore); rabbit anti-M-opsin (1:200, AB5405, Millipore); mouse anti-Brn3a (1:100, MAB1585, Millipore); mouse anti-Calbindin (1:500, CB300, Swant); goat anti-Otx2 (1:100, BAF1979, R&D Systems); mouse anti-Glutamine synthetase (1:500, 610517, BD Biosciences); rabbit anti-Pax6 (1:500, 901301, BioLegend); rabbit anti-γH2AX (1:500, ab2893, Abcam); and rat anti-BrdU (1:500, ab-6326, Abcam).

    Techniques: Staining